High Performance Liquid Chromatography (HPLC)
Shimadzu LC-20AD Liquid Chromatograph
The system is equipped with two binary solvent pumps, a built-in degasser, a column oven, an autosampler, and is controlled by LabSolutions Workstation software.
We also have a Pierce Reacti-Therm heating module for evaporating solvents as part of the sample preparation steps.
Methods Currently Available
Mycophenolic Acid & Mycophenolic Acid Glucuronide (MPA and MPAG)
Using a method modified from published literature, we are able to quantify mycophenolic acid and its glucuronide derivative from just 200 µL of plasma. This is currently being used for a pharmacogenomics/pharmacokinetics research study for Dr. Laneshia Tague.
Our analytical measuring range is
- 0.06 – 50.0 mg/L (MPA)
- 0.035 – 200.0 mg/L (MPAG)
Method Development
If you have a planned study with analytes that may be amenable to HPLC quantitation, please contact Dr. Jennifer Powers Carson (powers.jennifer.l@wustl.edu) to discuss feasibility and time frame of your study.